Pyrazinamide

पाइरेज़िनामाइड

Medically reviewed by Dr Rishikanth Shukla · 2026-08-04

What it is

Pyrazinamide is a medication used to treat active tuberculosis. It requires a prescription in India.

What it is used for

Pyrazinamide is used to treat active tuberculosis, a serious bacterial infection that primarily affects the lungs.

Active tuberculosis

How it works

Pyrazinamide works by killing or stopping the growth of certain bacteria that cause tuberculosis. It targets the bacteria directly, helping to clear the infection from the body.

How it is sold in India

In India Pyrazinamide comes as tablets, capsules and powder or sachet.

Common side effects

Most people have no side effects when taking Pyrazinamide. However, some may experience side effects such as nausea, vomiting, joint pain, or rash. Serious side effects like liver problems are rare but can occur.

See a doctor straight away if

Seek immediate medical attention if you experience signs of liver problems such as persistent nausea, vomiting, jaundice, or darkened urine. Also, if you have fever, vomiting, loss of appetite, joint pain, unusual bleeding, or difficulty urinating, contact your doctor right away.

Who should not take it

Do not take Pyrazinamide if you are allergic to pyrazinamide, niacin, ethionamide, or any other ingredients. Do not take it if you have severe liver disease. Do not take it if you have porphyria. Do not take it if you have hepatic impairment without monitoring. Do not take it if you have renal impairment without monitoring. Do not take it if you have diabetes mellitus without monitoring blood glucose. Do not take it if you have gout without consulting a doctor. Do not take it if you are pregnant or breastfeeding without consulting a doctor.

Questions people ask

Is it safe during pregnancy or while breastfeeding?

Consult your doctor before taking Pyrazinamide if you are pregnant or breastfeeding.

Is it safe if I have liver or kidney trouble?

Consult your doctor if you have liver or kidney trouble before taking Pyrazinamide.

What happens if I take too much?

Seek immediate medical attention if you suspect an overdose. Symptoms may include severe nausea, vomiting, and jaundice.

Brand names

140 medicines sold in India contain Pyrazinamide.

Brands sold in India include Pyzid, Unicox PZ, Pyzina, Zeena, Macrozide, P Zide, CAVIZIDE, Tbzide. Whichever name is on the strip, the medicine inside is the one described on this page.

Where this comes from

We do not publish doses. How much to take depends on your age, weight and other conditions — ask your doctor or pharmacist.

This page is general information, not medical advice, and it is not a substitute for seeing a doctor. It carries no dosage and no prices.